
- With Mayo Clinic endocrinologist
Todd B. Nippoldt, M.D.
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Todd B. Nippoldt, M.D.
Todd B. Nippoldt, M.D.
Dr. Todd Nippoldt is a board-certified specialist in internal medicine and endocrinology and metabolism. He has special expertise in the area of hormone disorders affecting the pituitary and adrenal glands as well as the testes and ovaries. He has been a member of the Mayo Clinic staff since 1988.
Dr. Nippoldt is a consultant in the Division of Endocrinology, Metabolism and Nutrition and works with patients who have disorders of the hormone-producing glands. Common disorders include diabetes, thyroid problems, osteoporosis and elevated cholesterol levels.
He also is involved in andrology, the study of male hormonal disorders, male infertility and sexual dysfunction and is an assistant professor of medicine at Mayo Clinic College of Medicine.
Dr. Nippoldt, a St. Paul, Minn., native, has also contributed to "Mayo Clinic Health Letter," a Mayo Clinic CD-ROM and the "Mayo Clinic Family Health Book." He is a fellow in the American College of Physicians and a member of the American Society of Reproductive Medicine, the American Society of Andrology, The Endocrine Society, The Pituitary Society and the American Association of Clinical Endocrinologists.
"I have found that those patients who have gone to the Internet and obtained accurate medical information come to their appointment with me very well informed, and the discussions regarding the evaluation and management of their condition are very productive and satisfying," he says.
"The key, however, is obtaining accurate medical information. As a medical editor for MayoClinic.com, I hope to be able to ensure that accurate, relevant and up-to-date information is available for patients and their families."
Causes (3)
- Male masturbation: Does frequency affect male fertility?
- Semen allergy: A cause of infertility?
- Abnormal sperm morphology: What does it mean?
Treatments and drugs (1)
- Fertility herbs and supplements: Do they enhance fertility?
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Abnormal sperm morphology: What does it mean?
My fiance recently had a semen analysis done. He was told he had abnormal sperm morphology. What does this mean? Can it be treated?
Answer
from Todd B. Nippoldt, M.D.
Sperm morphology is routinely evaluated as part of a standard semen analysis. Morphology refers to the size and shape of the sperm. The results of a sperm morphology exam indicate the percentage of sperm that appear normal when semen is viewed under a microscope. Abnormal sperm morphology may be a contributing factor in infertility.
Normal sperm have an oval head with a long tail. Abnormal sperm may have head or tail defects — such as a large or misshapen head or a crooked or double tail. These defects may impair the ability of the sperm to reach and fertilize an egg.
Causes of abnormal morphology include:
- Testicular abnormalities that are present at birth (congenital)
- Enlargement of veins within the scrotum (varicocele)
- High fever
- Illicit drug use
- Infections
The best recommendation is to repeat the semen analysis in four to six weeks to determine if the changes in morphology are temporary or permanent. Even with poor morphology, pregnancy may still be possible. Intrauterine insemination or in vitro fertilization methods are sometimes needed.
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