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Definition
By Mayo Clinic staffPreeclampsia is a condition of pregnancy marked by high blood pressure and excess protein in your urine after 20 weeks of pregnancy. Preeclampsia often causes only modest increases in blood pressure. Left untreated, however, preeclampsia can lead to serious — even fatal — complications for both you and your baby.
If you have preeclampsia, the only cure is delivery of your baby. If you're diagnosed with preeclampsia too early in your pregnancy for delivery to be an option, you and your doctor need to allow your baby more time to mature, without putting you or your baby at risk of serious complications.
- Pregnancy. National Heart Lung and Blood Institute. http://www.nhlbi.nih.gov/hbp/issues/preg/preg.htm. Accessed March 3, 2009.
- Conde-Agudelo A, et al. Maternal infection and risk of preeclampsia: Systematic review and metaanalysis. American Journal of Obstetrics and Gynecology. 2008;198:7.
- Bodnar LM, et al. Maternal vitamin D deficiency increases the risk of preeclampsia. The Journal of Clinical Endocrinology & Metabolism. 2007;92:3517.
- High blood pressure during pregnancy. March of Dimes. http://www.marchofdimes.com/printableArticles/188_1054.asp. Accessed Feb. 11, 2009.
- Norwitz ER, et al. Management of preeclampsia. http://www.uptodate.com/home/index.html. Accessed March 2, 2009.
- Leanos-Miranda A, et al. Urinary prolactin as a reliable marker for preeclampsia, its severity, and the occurrence of adverse pregnancy outcomes. Journal of Clinical Endocrinology Metabolism. 2008;93:2492.
- Fact sheets: High blood pressure during pregnancy. March of Dimes. http://www.marchofdimes.com/printableArticles/14332_1222.asp. Accessed Feb. 11, 2009.
- August P, et al. Clinical features, diagnosis and prognosis of preeclampsia. http://www.uptodate.com/home/index.html. Accessed March 2, 2009.
- Barton JR, et al. Prediction and prevention of recurrent preeclampsia. Obstetrics & Gynecology. 2008;112:359.
- Bellamy L, et al. Pre-eclampsia and risk of cardiovascular disease and cancer in later life: Systematic review and meta-analysis. British Medical Journal. 2007;335:974.
- Facchinetti F, et al. Migraine is a risk factor for hypertensive disorders in pregnancy: a prospective cohort study. Cephalgia: An International Journal of Headache. 2009;29:286.
