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Neurontin side effects: Is memory loss a concern?

Is memory loss a common side effect of Neurontin? Will my memory improve if I stop taking Neurontin?

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Mayo Clinic neurologist Jerry Swanson, M.D., and colleagues answer select questions from readers.

Answer

Gabapentin (Neurontin) is a medication used to help manage certain epileptic seizures and relieve pain in some painful conditions. The most common Neurontin side effects are dizziness and drowsiness. However, cognitive side effects, such as memory loss, also have been reported. Your memory may improve when you stop taking Neurontin.

If you're taking Neurontin for epilepsy and are experiencing memory problems, it is important to note that Neurontin is only one of several possible factors affecting memory in people with epilepsy. In fact, research shows that even the progression of epilepsy may affect memory.

Also, it's important to note that in January 2008, the Food and Drug Administration concluded that people taking anti-seizure (anti-epileptic) drugs, including Neurontin, have approximately twice the risk of suicidal thoughts and behavior as people who aren't taking the drug.

If you have questions about Neurontin or are experiencing troublesome side effects — including memory loss — that aren't going away, talk to your doctor. And be sure to talk to a doctor or counselor immediately if you are having suicidal thoughts.

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Nov 20, 2008