• image.alt
  • With Mayo Clinic cardiologist

    Martha Grogan, M.D.

    read biography

Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Question

Calcium supplements: A risk factor for heart attack?

I've read that calcium supplements may increase the risk of heart attack in older women. Is this true? I'm taking calcium supplements to treat osteopenia. My daily multivitamin also contains calcium. I wonder if I should stop taking calcium supplements?

Answer

from Martha Grogan, M.D.

Over the years, many studies have suggested that women who have a higher calcium intake experience not only improved bone health but also a lower risk of cardiovascular disease. One recent study, however, raised questions about the protective effect of calcium supplements on cardiovascular disease.

The study — which was published February 2008 in BMJ — was done primarily to evaluate the effect of calcium supplementation on bone density and bone fracture in elderly women. Later, however, the results were reanalyzed to note the occurrence of cardiac events among study participants. Although more heart attacks occurred in women who took calcium supplements, the statistical analysis indicated that the difference could have been due to chance. Also, a similar placebo-controlled study of calcium supplementation showed no increase in the risk of heart attack or other cardiovascular disease in women taking calcium.

Current recommendations regarding calcium supplementation haven't changed because of this study. As with any health issue, it's important to consult your doctor to determine what's best in your case. Many factors may influence your specific needs for calcium.

Next question
CRP level: A risk factor for heart disease?
References
  1. Grogan M (expert opinion). Mayo Clinic, Rochester, Minn. June 8, 2008.
  2. Bolland MJ, et al. Vascular events in healthy older women receiving calcium supplementation: Randomised controlled trial. BMJ. 2008;336(7638):262-266.
  3. Biggs WS. Calcium supplementation: Data were misrepresented. BMJ. 2008;336(7641):404.
  4. Lappe JM, et al. Calcium supplementation: Results may not be generalisable. BMJ. 2008;336(7641):403.

AN01928

Oct. 28, 2008

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger