Aspirin allergy: What are the symptoms?

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    James T. Li, M.D.

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Question

Aspirin allergy: What are the symptoms?

I think I may have an aspirin allergy. What are the symptoms?

Answer

from James T. Li, M.D.

It's possible to have a sensitivity to aspirin. In fact, aspirin can cause a severe asthma attack — especially in people who have asthma or sinus problems. Reactions to aspirin are often related to the drug itself, however, rather than to an allergic or immunological response to the drug.

Signs and symptoms of aspirin sensitivity — which usually occur within a few hours of taking the medication — range from mild to serious and may include:

  • Hives
  • Itchy skin
  • Runny nose
  • Swelling of the lips, tongue or face
  • Coughing, wheezing or shortness of breath

If you've had a reaction to aspirin, avoid all forms of aspirin. It's also best to avoid other nonsteroidal anti-inflammatory drugs (NSAIDs) as well, including ibuprofen (Advil, Motrin, others) and naproxen (Aleve, others). Keep in mind that aspirin and other NSAIDs are found in many over-the-counter medications — so check labels carefully.

If you think you might have an aspirin sensitivity, consult your doctor or allergist for advice. Rarely, aspirin can cause a life-threatening reaction.

References
  1. Solomon DH. Patient information: Nonsteroidal antiinflammatory drugs (NSAIDs). http://www.uptodate.com/home/index.html. Accessed Aug. 20, 2008.
  2. Aspirin/NSAID sensitivity. American Academy of Allergy, Asthma & Immunology. http://www.aaaai.org/patients/advocate/2004/winter/aspirin.stm. Accessed Aug. 20, 2008.

AN01467

Nov. 5, 2008

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