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Angiotensin-converting enzyme (ACE) inhibitors
ACE inhibitors treat a variety of conditions, such as high blood pressure, scleroderma and migraines. Find out more about this class of medication.
By Mayo Clinic staffAngiotensin-converting enzyme (ACE) inhibitors help relax blood vessels. ACE inhibitors prevent an enzyme in your body from producing angiotensin II, a substance in your body that affects your cardiovascular system by narrowing your blood vessels and releasing hormones that can raise your blood pressure. This narrowing can cause high blood pressure and force your heart to work harder.
Examples of ACE inhibitors
Several ACE inhibitors are available. Which one is best for you depends on your health and the condition being treated.
Examples of ACE inhibitors include:
- Benazepril (Lotensin)
- Captopril (Capoten)
- Enalapril (Vasotec)
- Fosinopril (Monopril)
- Lisinopril (Prinivil, Zestril)
- Moexipril (Univasc)
- Perindopril (Aceon)
- Quinapril (Accupril)
- Ramipril (Altace)
- Trandolapril (Mavik)
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References
- Reeder GS. Angiotensin converting enzyme inhibitors and receptor blockers in acute myocardial infarction: Recommendations for use. http://www.uptodate.com/home/index. Accessed Nov. 13, 2008.
- Colucci WS. Angiotensin converting enzyme inhibitors and receptor blockers in heart failure: Mechanisms of action. http://www.uptodate.com/home/index. Accessed Nov. 13, 2008.
- Chobanian AV, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. New England Journal of Medicine. 2003;289:2560.
- Initial antihypertensive therapy: Drugdex Consults. Micromedex Healthcare Series. http://www.micromedex.com/. Accessed Nov. 12, 2008.
- Blood pressure-lowering drugs. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=159. Accessed Nov. 12, 2008.
- Sheps SG, ed. Mayo Clinic 5 Steps to Controlling High Blood Pressure. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2008:189.
